This randomized clinical trial investigates the preliminary finding that the sweet-liking phenotype interacts with a high level of craving for alcohol to improve the response to naltrexone in patients with alcohol dependence.
This 12-week, double-blind, randomized clinical trial of naltrexone vs placebo in individuals with alcohol dependence does not support the hypothesis that the Asp40 allele moderates the response to naltrexone treatment.
Kühn and colleagues investigate the effect of alcohol abstinence on neuronal plasticity measured as longitudinal volume change in distinct hippocampal subfields.
Gustafson et al determine whether patients leaving residential treatment for alcohol use disorders with a smartphone application to support recovery have fewer risky drinking days than control patients.
Crum et al used data from the National Epidemiologic Survey on Alcohol and Related Conditions to evaluate the hypothesis that alcohol self-medication of mood symptoms increases the probability of subsequent onset and the persistence or chronicity of alcohol dependence.