This study identifies a potential systems-level intermediate phenotype linked to emotion processing in schizophrenia and examines the psychological association, task specificity, test-retest reliability, and clinical validity of the identified phenotype.
This Viewpoint suggests that the assertion that prolonged exposure or cognitive processing therapy should be the dominant evidence-based treatments for war-related PTSD is simplistic and may at times be unhelpful or contraindicated.
This analysis of a randomized clinical trial tests the moderating role of pretreatment executive function, severity of anxiety, and severity of medical comorbidity in remission of treatment-resistant late-life depression after aripiprazole augmentation.
This Finnish national birth cohort study assesses the association of childhood bullying and/or exposure to bullying with subsequent psychiatric outcomes and diagnoses made during adolescence or adulthood.
This study compares mental health symptom monitoring alone vs symptom monitoring plus care management among 1018 older, community-dwelling, low-income adults prescribed an antidepressant or anxiolytic and experiencing clinically significant mental health symptoms at intake.
This pooling of individual-level data from a series of large general population–based cohort studies examines the association between psychological distress and the risk of completed suicide.
This survey of 3 cohorts of women veterans from the Vietnam era assesses whether lifetime and current prevalence of posttraumatic stress disorder vary by location of service, with adjustment for demographics, military service, and wartime exposures.
This Viewpoint discusses the use of fibroblast growth factor 2 as an adjunct for treating anxiety.
This Neuroscience and Psychiatry article discusses the role in social anxiety of a novel disrupted regulatory sequence in serotonin neurochemistry resulting from overactive serotonin signaling.
This randomized clinical trial examines whether d-cycloserine augments cognitive behavioral therapy in the treatment of obsessive-compulsive disorder (OCD) and whether concomitant use of antidepressants moderates the effects of d-cycloserine.
This meta-analysis shows that various reporting biases are present for trials on the efficacy of US Food and Drug Administration–approved second-generation antidepressants for anxiety disorders.
This meta-analysis suggests that mental disorders rank among the most important causes of death worldwide.
This neuroimaging study suggests that abnormal uncinate fasciculus and cingulum white matter structure may underlie emotional, but not behavioral, dysregulation in pediatric psychiatric disorders.
This multicenter, prospective cohort study provides support for the deleterious effect of elevated amyloid-β levels on cognitive function in preclinical Alzheimer disease.
Waszczuk and colleagues investigated the phenotypic associations between depression and anxiety disorder symptom subscales and tested the genetic structures underlying these symptoms (DSM-5–related, unidimensional and bidimensional) across 3 developmental stages: childhood, adolescence, and early adulthood.
Grant et al determine aspects of claims processes that claimants to transport accident and workers’ compensation schemes find stressful and whether such stressful experiences are associated with poorer long-term recovery.
Ginsburg et al determine whether acute clinical improvement and treatment type (ie, cognitive behavioral therapy, sertraline, or their combination predicted remission of anxiety and improvement in global functioning at a mean of 6 years after randomization and examine predictors of outcomes at follow-up.