This longitudinal, population-based study investigates whether differences in cardiac autonomic function as indexed by resting heart rate and blood pressure are associated with psychiatric disorders during the lifetime of men in Sweden.
This population-based study uses data from the Zurich Cohort Study to assess the persistence of mental health disorders in adults using 7 interviews conducted across 29 years in Switzerland.
This article analyzes the mechanisms of harm-avoidance learning as a potential model for obsessive-compulsive disorder.
This Viewpoint argues that individualized exposure therapy distinguishing between fear of food vs weight gain is important for successful management of anorexia nervosa.
This population-based case-control cohort study examines the risk for psychiatric and neurodevelopmental disorders among the full siblings of probands with autism spectrum disorder.
This cohort study uses national survey data to examine associations between cannabis use and risk of mental health and substance use disorders in the general US adult population.
This study uses data from the Avon Longitudinal Study of Parents and Children to investigate the association of genetic risk for schizophrenia with different phenotypes in a population-based birth cohort of adolescents.
This cohort study, using a national longitudinal registry, estimates mortality risk of persons with obsessive-compulsive disorder compared with those without this disorder.
This pooling of individual-level data from a series of large general population–based cohort studies examines the association between psychological distress and the risk of completed suicide.
This Editorial discusses the use of antipsychotic medications for indications other than psychosis in young people who do not have psychosis.
This meta-analysis shows that various reporting biases are present for trials on the efficacy of US Food and Drug Administration–approved second-generation antidepressants for anxiety disorders.
This cross-sectional study demonstrates that psychiatric comorbidities are common among individuals with Tourette syndrome and that most comorbidities begin early in life.
This retrospective quantification and assessment of temporal patterns of DSM-IV diagnoses not otherwise specified among youth finds that subthreshold diagnoses have expanded, a trend that will continue in the DSM-5 era.
This longitudinal study determines that response to cognitive behavioral therapy (CBT) can be predicted on an individual-patient level based on functional neuroimaging data in panic disorder and agoraphobia.
This prospective longitudinal study provides evidence that structural abnormalities in anterior insula volume are related to the neurobiology of depressive disorders starting in early childhood.
Waszczuk and colleagues investigated the phenotypic associations between depression and anxiety disorder symptom subscales and tested the genetic structures underlying these symptoms (DSM-5–related, unidimensional and bidimensional) across 3 developmental stages: childhood, adolescence, and early adulthood.
Ginsburg et al determine whether acute clinical improvement and treatment type (ie, cognitive behavioral therapy, sertraline, or their combination predicted remission of anxiety and improvement in global functioning at a mean of 6 years after randomization and examine predictors of outcomes at follow-up.
Khan et al assessed mortality risk among adult patients with a diagnosis of schizophrenia, depression, bipolar disorder, anxiety disorder, or attention-deficit/hyperactivity disorder participating in clinical trials and evaluated if psychopharmacological agents worsen this risk.