This population-based study evaluates the presence and burden of autistic spectrum disorder traits in individuals with neurofibromatosis type 1.
This population-based case-control cohort study examines the risk for psychiatric and neurodevelopmental disorders among the full siblings of probands with autism spectrum disorder.
This cohort study examines whether quantified neural function in social perception circuits can serve as an individual-level marker of autism spectrum disorder in children and adolescents.
This exome sequencing study of family members with bipolar disorder from 8 multiplex families tested rare, segregating variants in 3 independent samples, followed by association testing in a large case-control meta-analysis.
This population-based cohort study of children with autism confirms previous findings that children born by cesarean section are approximately 20% more likely to be diagnosed as having autism, although this association is likely due to familial confounding.
This resting-state functional magnetic resonance imaging study compares the intrinsic functional connectivity between brain networks in a large sample of individuals with autism spectrum disorder and typically developing control subjects.
This fMRI study determines differences in brain responses, habituation, and connectivity during exposure to mildly aversive sensory stimuli in youth with autism spectrum disorders (ASDs) and sensory overresponsivity (SOR) compared with youth with ASDs without SOR and control subjects.
This population-based twin study estimates that the liability to autism spectrum disorder derives primarily from additive genetic and to a lesser extent nonshared environmental effects.
In this large prospective cohort study, gastrointestinal symptoms were more common and persistent in children with autism spectrum disorder compared with children with typical development or developmental delay.
This proof-of-principle study demonstrated that genomic biomarkers with very good sensitivity and specificity for boys with autism spectrum disorder in general pediatric settings can be identified.
The findings of this large Canadian multisite longitudinal study confirm the heterogeneous nature of developmental trajectories in autism spectrum disorder,
Lyall and coauthors examine the familiality of Social Responsiveness Scale scores of individuals with and without autism spectrum disorder.
Fishman and colleagues investigate whether adolescents with autism spectrum disorder show altered functional connectivity in 2 brain networks putatively impaired in autism spectrum disorder and involved in social processing, the mentalizing theory of mind and mirror neuron systems.
Goh and colleagues assess brain lactate in individuals with autism spectrum disorder and typically developing controls using high-resolution, multiplanar spectroscopic imaging, and map the distribution of lactate in the brains of individuals with autism spectrum disorder, assessing correlations of elevated brain lactate with age, autism subtype, and intellectual ability.
Maenner and colleagues aimed to assess potential effects of the DSM-5 autism spectrum disorder (ASD) criteria on ASD prevalence estimation by retrospectively applying the new criteria to population-based surveillance data collected for previous ASD prevalence estimation.
Ludvigsson and coauthors examine the association between autism spectrum disorders and celiac disease.
D’Onofrio et al estimate the extent to which the associations between early gestational age and offspring mortality and morbidity are the result of confounding factors in a population-based cohort study.
Uddin and coauthors examine whether specific networks can distinguish children with autism spectrum disorder from typically developing children.