This 2-year observational cohort study investigates whether lower midbrain serotonin transporter binding potential predicts future suicide attempts, intent, and lethality in patients with major depressive disorder.
This cohort study examines whether quantified neural function in social perception circuits can serve as an individual-level marker of autism spectrum disorder in children and adolescents.
This study uses data from the Philadelphia Neurodevelopmental Cohort to evaluate the charting of brain intrinsic connectivity network patterns to serve as a measure of attention functioning in youth.
This Viewpoint discusses steps to accelerate innovation and advance new medicines for psychiatric disease.
This cohort study evaluates the association of predeployment heart rate variability with risk of posttraumatic stress disorder after deployment in US Marines.
This study suggests that hemispheric specialization could serve as a potential imaging biomarker of schizophrenia.
This proof-of-principle study demonstrated that genomic biomarkers with very good sensitivity and specificity for boys with autism spectrum disorder in general pediatric settings can be identified.
This prospective longitudinal study provides evidence that structural abnormalities in anterior insula volume are related to the neurobiology of depressive disorders starting in early childhood.
Chiappelli et al investigate whether the level of KYNA changes following psychological stress and whether this change is associated with stress-related behavior. Javitt provides commentary in a related editorial.
Eraly et al evaluate whether plasma concentration of the inflammatory marker C-reactive protein helps to predict posttraumatic stress disorder symptoms.
In a methylome-wide association study, Aberg and coauthors identify schizophrenia DNA methylation biomarkers in the blood.
McGrath et al identify a candidate neuroimaging treatment-specific biomarker that predicts differential outcome to either medication or psychotherapy.
This cohort study examines risk for depression in children and grandchildren stratified by biological parents’ and grandparents’ depression status.