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  • Short-term Suicide Risk After Psychiatric Hospital Discharge

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    JAMA Psychiatry. 2016; doi: 10.1001/jamapsychiatry.2016.2035

    This longitudinal cohort study uses data from the National Medicaid Analytic Extract and the National Center for Health Statistics to assess the postdischarge risk for suicide among psychiatric inpatients.

  • Use of Antipsychotics During Pregnancy: Pregnant Women Get Sick—Sick Women Get Pregnant

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    JAMA Psychiatry. 2016; 73(9):901-903. doi: 10.1001/jamapsychiatry.2016.1538
  • Triggers for Violent Criminality in Patients With Psychotic Disorders

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    JAMA Psychiatry. 2016; 73(8):796-803. doi: 10.1001/jamapsychiatry.2016.1349

    This study uses Swedish national registry data to identify triggers for violent behavior in patients with schizophrenia spectrum and bipolar disorders, and to compare risk in those populations vs healthy controls.

  • Polygenic Risk of Psychosis and Ventral Striatal Activation During Reward Processing in Healthy Adolescents

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    JAMA Psychiatry. 2016; 73(8):852-861. doi: 10.1001/jamapsychiatry.2016.1135

    This cross-sectional study examines whether common risk variants for psychosis are associated with individual variation in the ventral striatum.

  • The Salience of Reward

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    JAMA Psychiatry. 2016; 73(8):777-778. doi: 10.1001/jamapsychiatry.2016.1134
  • Promising 2-Pronged Approach to Genetic Basis of Bipolar Disorder

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    JAMA Psychiatry. 2016; 73(6):553-554. doi: 10.1001/jamapsychiatry.2016.0298
  • Exome Sequencing of Familial Bipolar Disorder

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    JAMA Psychiatry. 2016; 73(6):590-597. doi: 10.1001/jamapsychiatry.2016.0251

    This exome sequencing study of family members with bipolar disorder from 8 multiplex families tested rare, segregating variants in 3 independent samples, followed by association testing in a large case-control meta-analysis.

  • Self-harm, Unintentional Injury, and Suicide in Bipolar Disorder During Maintenance Mood Stabilizer Treatment: A UK Population-Based Electronic Health Records Study

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    JAMA Psychiatry. 2016; 73(6):630-637. doi: 10.1001/jamapsychiatry.2016.0432

    This longitudinal cohort study compares rates of self-harm, unintentional injury, and suicide in patients with bipolar disorder prescribed lithium, valproate sodium, olanzapine, or quetiapine fumarate.

  • Observed Cognitive Performance and Deviation From Familial Cognitive Aptitude at Age 16 Years and Ages 18 to 20 Years and Risk for Schizophrenia and Bipolar Illness in a Swedish National Sample

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    JAMA Psychiatry. 2016; 73(5):465-471. doi: 10.1001/jamapsychiatry.2016.0053

    This cohort study determines whether the developmental processes that predispose to schizophrenia are better reflected by the observed cognitive performance in adolescence or the deviation of that performance from an individual’s familial cognitive aptitude.

  • Patterns of Nonrandom Mating Within and Across 11 Major Psychiatric Disorders

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    JAMA Psychiatry. 2016; 73(4):354-361. doi: 10.1001/jamapsychiatry.2015.3192

    This cohort study using Swedish population registers quantifies the nature and extent of nonrandom mating, within and across a broad range of psychiatric conditions, at the population level.

  • Use of Lithium and Anticonvulsants and the Rate of Chronic Kidney Disease: A Nationwide Population-Based Study

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    JAMA Psychiatry. 2015; 72(12):1182-1191. doi: 10.1001/jamapsychiatry.2015.1834

    This cohort study examines rates of chronic kidney disease in relation to use of lithium, anticonvulsants, and other drugs for treatment of bipolar disorder.

  • The Safety of Lithium

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    JAMA Psychiatry. 2015; 72(12):1167-1169. doi: 10.1001/jamapsychiatry.2015.2014
  • Treatment of Young People With Antipsychotic Medications in the United States

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    JAMA Psychiatry. 2015; 72(9):867-874. doi: 10.1001/jamapsychiatry.2015.0500

    This population-level observational study reports increased use of antipsychotic medication from 2006 to 2010 in adolescents and young adults, but not in children 12 years or younger.

  • Antipsychotic Use in Youth Without Psychosis: A Double-edged Sword

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    JAMA Psychiatry. 2015; 72(9):859-860. doi: 10.1001/jamapsychiatry.2015.0632

    This Editorial discusses the use of antipsychotic medications for indications other than psychosis in young people who do not have psychosis.

  • State-Dependent Differences in Emotion Regulation Between Unmedicated Bipolar Disorder and Major Depressive Disorder

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    JAMA Psychiatry. 2015; 72(7):687-696. doi: 10.1001/jamapsychiatry.2015.0161

    This cross-sectional study reports that medication-free patients with major depressive disorder vs bipolar disorder appear to differ in brain activations during emotion regulation, both while depressed and in remission.

  • Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

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    JAMA Psychiatry. 2015; 72(7):642-650. doi: 10.1001/jamapsychiatry.2015.0554

    This genome-wide association analysis identifies a novel locus for neuroticism and shows polygenic association with major depressive disorder (MDD).

  • Circuit- and Diagnosis-Specific DNA Methylation Changes at γ-Aminobutyric Acid–Related Genes in Postmortem Human Hippocampus in Schizophrenia and Bipolar Disorder

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    JAMA Psychiatry. 2015; 72(6):541-551. doi: 10.1001/jamapsychiatry.2015.49

    This epigenetic association study investigates whether aberrant DNA methylation contributes to circuit- and diagnosis-specific abnormal expression of GAD1 regulatory network genes in schizophrenia and bipolar disorder.

  • Risks for Nonaffective Psychotic Disorder and Bipolar Disorder in Young People With Autism Spectrum Disorder: A Population-Based Study

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    JAMA Psychiatry. 2015; 72(5):483-489. doi: 10.1001/jamapsychiatry.2014.3059

    This nested case-control study reports a substantially increased risk for nonaffective psychotic disorder and bipolar disorder in individuals with an early diagnosis of autism spectrum disorder (ASD).

  • Mortality in Mental Disorders and Global Disease Burden Implications: A Systematic Review and Meta-analysis

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    JAMA Psychiatry. 2015; 72(4):334-341. doi: 10.1001/jamapsychiatry.2014.2502

    This meta-analysis suggests that mental disorders rank among the most important causes of death worldwide.

  • White Matter Structure in Youth With Behavioral and Emotional Dysregulation Disorders: A Probabilistic Tractographic Study

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    JAMA Psychiatry. 2015; 72(4):367-376. doi: 10.1001/jamapsychiatry.2014.2170

    This neuroimaging study suggests that abnormal uncinate fasciculus and cingulum white matter structure may underlie emotional, but not behavioral, dysregulation in pediatric psychiatric disorders.