This meta-analysis of trials comparing collaborative to usual care in adults with depression uses individual participant data to investigate if chronic comorbidities modify the effects of the intervention.
This study investigates childhood risk factors and functioning in young adults with persistent, remitted, and late-onset ADHD.
This longitudinal cohort study compares rates of self-harm, unintentional injury, and suicide in patients with bipolar disorder prescribed lithium, valproate sodium, olanzapine, or quetiapine fumarate.
This genome-wide association study assesses analyses from 3 studies of substance use disorder genetics to identify DSM-IV criteria for cannabis dependence in a large African American and European American cohort.
This analysis of a randomized clinical trial tests the moderating role of pretreatment executive function, severity of anxiety, and severity of medical comorbidity in remission of treatment-resistant late-life depression after aripiprazole augmentation.
This cohort study, using a national longitudinal registry, estimates mortality risk of persons with obsessive-compulsive disorder compared with those without this disorder.
This cohort study examines the association between eating disorders and suicide attempts, with further analyses of familial associations as risk factors.
This study uses data from the Avon Longitudinal Study of Parents and Children to investigate the association of genetic risk for schizophrenia with different phenotypes in a population-based birth cohort of adolescents.
This study of World Mental Healthy Surveys from 17 countries investigates the association between mental disorders and the subsequent development of chronic physical diseases.
This international cohort study assesses the effects of the 16p11.2 duplication on cognitive, behavioral, medical, and anthropometric traits in carriers and compared these findings with effects in 16p11.2 deletion carriers and the relatives of both groups.
This survey study presents nationally representative findings on the prevalence, correlates, psychiatric comorbidity, disability, and treatment of DSM-5 drug use disorder diagnoses overall and by severity level.
This cohort study reports on the magnitude of the association between attempted suicide and epilepsy.
This meta-analysis of whole-brain structural neuroimaging studies of youths with conduct problems identifies gray matter reductions within the insula, amygdala, and frontal and temporal regions.
Among 75 medication-free patients with remitted major depressive disorder and no relevant comorbidity, this prospective cohort study tests the hypothesis that RSATL-SCSR connectivity for self-blaming relative to other-blaming emotions predicts subsequent recurrence of depressive episodes.
This national epidemiologic survey finds that alcohol use disorder is highly prevalent, highly comorbid, and disabling, with an urgent need for education of the public and policy makers, destigmatization of the disorder, and encouragement of those with the disorder to seek treatment.
To examine the direct and indirect relationships between perceived racial discrimination and common forms of psychopathology, 12 common diagnoses were assessed in a nationally representative sample of African American and Afro-Caribbean adults.
This genome-wide association analysis identifies a novel locus for neuroticism and shows polygenic association with major depressive disorder (MDD).
This randomized clinical trial in patients with comorbid adult attention-deficit/hyperactivity disorder (ADHD) and cocaine use disorder examined whether extended-release mixed amphetamine salts are effective for both improving symptoms of ADHD and reducing cocaine use.
This population-based cohort study reports an independent association of depression and diabetes mellitus (DM) with the risk for dementia in a national population sample from medical registries. See also the Invited Commentary by Reynolds.