This meta-analysis of trials comparing collaborative to usual care in adults with depression uses individual participant data to investigate if chronic comorbidities modify the effects of the intervention.
This pooling of individual-level data from a series of large general population–based cohort studies examines the association between psychological distress and the risk of completed suicide.
This study of World Mental Healthy Surveys from 17 countries investigates the association between mental disorders and the subsequent development of chronic physical diseases.
This national epidemiologic survey finds that alcohol use disorder is highly prevalent, highly comorbid, and disabling, with an urgent need for education of the public and policy makers, destigmatization of the disorder, and encouragement of those with the disorder to seek treatment.
Bryan and Clemans determined whether suicide risk is more frequent and heightened among deployed military personnel with multiple lifetime traumatic brain injuries (TBIs) than among those with no TBIs or a single TBI.
Ilgen et al examine the associations between clinical diagnoses of noncancer pain and suicide during a 1-year period in 4 863 086 individuals receiving care through the US Department of Veterans Healthcare System.
Chiappelli et al investigate whether the level of KYNA changes following psychological stress and whether this change is associated with stress-related behavior. Javitt provides commentary in a related editorial.
This randomized clinical trial evaluates the use of N-acetylcysteine in short-term treatment of skin-picking disorder.
This study identifies a potential systems-level intermediate phenotype linked to emotion processing in schizophrenia and examines the psychological association, task specificity, test-retest reliability, and clinical validity of the identified phenotype.
This nonrandomized trial compares the effects of an intervention comprising manual-guided sessions on health care engagement and health information technology use vs usual care on self-reported substance use and depression.
This randomized clinical trial compares the efficacy of cognitive behavioral group psychotherapy vs individual clinical management and methylphenidate vs placebo in patients with adult attention-deficit/hyperactivity disorder.
This randomized clinical trial assesses the efficacy of sertraline treatment vs placebo in preventing depressive disorders following traumatic brain injury.