This meta-analysis of trials comparing collaborative to usual care in adults with depression uses individual participant data to investigate if chronic comorbidities modify the effects of the intervention.
This meta-analysis examines individual patient data to discover the efficacy of mindfulness-based cognitive therapy compared with usual care and other active treatments, including antidepressants, in treating those with recurrent depression.
This network meta-analysis assesses the efficacy of all antipsychotics used in patients with treatment-resistant schizophrenia.
This randomized trial suggests that the type of family therapy matters in the treatment of adolescent-onset anorexia nervosa.
This meta-analysis of 6 placebo-controlled studies examines whether the baseline severity of schizophrenia influences the efficacy of antipsychotic drugs.
This meta-analysis reports that the average treatment change associated with placebo treatment in antipsychotic trials increased since 1960, while the change associated with medication treatment decreased.
The SALOME randomized clinical trial tests if injectable hydromorphone is noninferior to injectable diacetylmorphine in reducing illicit heroin use after 6 months of intervention.
Weisz et al conduct a meta-analysis of 52 randomized trials directly comparing evidence-based
psychotherapies with usual clinical care for psychopathology in children and adolescents. See also
the editorial by