This cross-sectional positron emission tomography study describes an overactive presynaptic serotonin system, with increased serotonin synthesis and transporter availability, in patients with social anxiety disorder.
This 22-year longitudinal study reports that women with highest number of symptoms of posttraumatic stress disorder had a nearly 2-fold increased risk of type 2 diabetes mellitus over follow-up than women with no trauma exposure.
This 2-year observational cohort study investigates whether lower midbrain serotonin transporter binding potential predicts future suicide attempts, intent, and lethality in patients with major depressive disorder.
This cross-sectional study examines whether common risk variants for psychosis are associated with individual variation in the ventral striatum.
Khandaker et al test the hypothesis that higher serum levels of interleukin 6 and C-reactive protein in childhood would increase future risks for depression and psychosis.
This laboratory-based cross-sectional study assesses cue-induced craving for cocaine in adults using both subjective and objective indices of cue-elicited responses.
In an observational, longitudinal study, Judd and coauthors determine the prevalence of overtly expressed irritability/anger and its effect on intake presentation and the long-term course of illness.
This cross-sectional study reports an increase in spontaneous gamma activity during auditory steady-state stimulation in schizophrenia, reflecting a disruption in the normal balance of excitation and inhibition.
This cross-sectional study reports that global differences in gray matter volume may be due to alterations in the general mechanisms underlying normal brain development in attention-deficit/hyperactivity disorder.
This cross-sectional study reports that medication-free patients with major depressive disorder vs bipolar disorder appear to differ in brain activations during emotion regulation, both while depressed and in remission.
This case-control study finds that cocaine addiction is associated with disturbed resting-state functional connectivity in several specific striatal-cortical circuits.
This case-control cross-sectional study finds that short-term treatment with antipsychotics was associated with prefrontal cortical thinning, but that treatment was associated with better cognitive control and increased prefrontal functional activity.
Eraly et al evaluate whether plasma concentration of the inflammatory marker C-reactive protein helps to predict posttraumatic stress disorder symptoms.