This randomized clinical trial assesses the efficacy of sertraline treatment vs placebo in preventing depressive disorders following traumatic brain injury.
This 2-year observational cohort study investigates whether lower midbrain serotonin transporter binding potential predicts future suicide attempts, intent, and lethality in patients with major depressive disorder.
This nationwide cohort study investigates whether the use of hormonal contraception is positively associated with subsequent use of antidepressants and a diagnosis of depression among women in Denmark.
This longitudinal cohort study uses data from the National Medicaid Analytic Extract and the National Center for Health Statistics to assess the postdischarge risk for suicide among psychiatric inpatients.
This Editorial discusses the effectiveness of short-term psychodynamic psychotherapy for major depressive disorder.
This randomized clinical trial explores whether dynamic psychotherapy is not inferior to cognitive therapy in the treatment of major depressive disorder among adults treated in a community mental health center.
This cohort study examines risk for depression in children and grandchildren stratified by biological parents’ and grandparents’ depression status.
This meta-analysis of trials comparing collaborative to usual care in adults with depression uses individual participant data to investigate if chronic comorbidities modify the effects of the intervention.
This cohort study evaluates associations between self-reported physical and emotional abuse in childhood and all-cause mortality rates in adult women.
This randomized clinical trial tests whether whole-body hyperthermia has specific antidepressant effects when compared with a sham treatment.
This meta-analysis of randomized and observational studies reports comparison of neonatal outcomes among women with untreated antenatal depression vs no depression.
This nonrandomized trial compares the effects of an intervention comprising manual-guided sessions on health care engagement and health information technology use vs usual care on self-reported substance use and depression.
This randomized clinical trial evaluates the safety and efficacy of basimglurant modified-release vs placebo as adjunctive therapy to ongoing antidepressant medication therapy in patients with major depressive disorder who had inadequate response within the current episode.
This longitudinal cohort study examines suicide attempt risk factors, methods, and timing among soldiers currently deployed, previously deployed, and never deployed.
This randomized trial compares the efficacy of targeted complicated grief treatment, citalopram, both, or neither on the outcomes of patients with complicated grief.
This study assesses whether certain factors identified with structural magnetic resonance imaging techniques are able to predict response to electroconvulsive therapy in patients with major depressive disorder.
This meta-analysis examines individual patient data to discover the efficacy of mindfulness-based cognitive therapy compared with usual care and other active treatments, including antidepressants, in treating those with recurrent depression.