This Special Communication examines the degree to which modern operationalized diagnostic criteria for schizophrenia reflect the main clinical features of the disorder as described historically by diagnostic experts.
This study identifies a potential systems-level intermediate phenotype linked to emotion processing in schizophrenia and examines the psychological association, task specificity, test-retest reliability, and clinical validity of the identified phenotype.
This study determines the neural correlates of disturbed body awareness in borderline personality disorder and its associations with emotional dysregulation.
Among 75 medication-free patients with remitted major depressive disorder and no relevant comorbidity, this prospective cohort study tests the hypothesis that RSATL-SCSR connectivity for self-blaming relative to other-blaming emotions predicts subsequent recurrence of depressive episodes.
This fMRI study determines differences in brain responses, habituation, and connectivity during exposure to mildly aversive sensory stimuli in youth with autism spectrum disorders (ASDs) and sensory overresponsivity (SOR) compared with youth with ASDs without SOR and control subjects.
This cross-sectional study reports that medication-free patients with major depressive disorder vs bipolar disorder appear to differ in brain activations during emotion regulation, both while depressed and in remission.
This Neuroscience and Psychiatry article proposes that changing levels of estradiol may directly modify the activity of dorsal and ventral emotional regulation nodes and circuits, modifying the cognitive and emotional consequences of life stress and leading to depression in women.
This neuroimaging study suggests that abnormal uncinate fasciculus and cingulum white matter structure may underlie emotional, but not behavioral, dysregulation in pediatric psychiatric disorders.
This randomized clinical trial shows that cognitive behavior therapy that includes exposure therapy to treat prolonged grief disorder facilitates emotional responses that reduce symptoms.
In a 2-center cross-sectional study, Redlich et al investigate and compare morphometric changes in unipolar depression (UD) and bipolar depression (BD), and replicate the findings at 2 independent neuroimaging sites. They conclude that individuals with UD and those with BD are differentiated by structural abnormalities in neural regions supporting emotion processing.
Wegbreit et al test the hypothesis that youth with BD (<18 years) would show greater convergence of amygdala hyperactivation and prefrontal cortical hypoactivation vs adults with BD. PubMed and PsycINFO databases were searched for original, task-related coordinate-based fMRI articles. GingerALE software was used to compared pediatric and adult findings.
Moeller and coauthors investigate the neural correlates of impaired insight in addiction using a combined functional magnetic resonance imaging and voxel-based morphometry approach.
Bebko et al identify neuroimaging measures that are associated with behavioral and emotional dysregulation pathologic dimensions in a multisite cohort of youth. Leibenluft provides an invited commentary
To examine whether early child care moderates associations between maternal depressive symptoms and child internalizing problems (emotional problems, separation anxiety symptoms, and social withdrawal symptoms) during the preschool period, Herba et al performed a population-based prospective cohort study within the Québec Longitudinal Study of Child Development.