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  • Positron Emission Tomographic Imaging of the Serotonergic System and Prediction of Risk and Lethality of Future Suicidal Behavior

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    JAMA Psychiatry. 2016; 73(10):1048-1055. doi: 10.1001/jamapsychiatry.2016.1478

    This 2-year observational cohort study investigates whether lower midbrain serotonin transporter binding potential predicts future suicide attempts, intent, and lethality in patients with major depressive disorder.

  • Improving Prediction of Suicide and Accidental Death After Discharge From General Hospitals With Natural Language Processing

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    JAMA Psychiatry. 2016; 73(10):1064-1071. doi: 10.1001/jamapsychiatry.2016.2172

    This health care use study examines the extent to which incorporating natural language processing of narrative discharge notes improves stratification of risk for death by suicide after medical or surgical hospital discharge.

  • Association of Reports of Childhood Abuse and All-Cause Mortality Rates in Women

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    JAMA Psychiatry. 2016; 73(9):920-927. doi: 10.1001/jamapsychiatry.2016.1786

    This cohort study evaluates associations between self-reported physical and emotional abuse in childhood and all-cause mortality rates in adult women.

  • Examination of the Effects of an Intervention Aiming to Link Patients Receiving Addiction Treatment With Health Care: The LINKAGE Clinical Trial

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    JAMA Psychiatry. 2016; 73(8):804-814. doi: 10.1001/jamapsychiatry.2016.0970

    This nonrandomized trial compares the effects of an intervention comprising manual-guided sessions on health care engagement and health information technology use vs usual care on self-reported substance use and depression.

  • Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse: An Individual Patient Data Meta-analysis From Randomized Trials

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    JAMA Psychiatry. 2016; 73(6):565-574. doi: 10.1001/jamapsychiatry.2016.0076

    This meta-analysis examines individual patient data to discover the efficacy of mindfulness-based cognitive therapy compared with usual care and other active treatments, including antidepressants, in treating those with recurrent depression.

  • Mortality Among Persons With Obsessive-Compulsive Disorder in Denmark

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    JAMA Psychiatry. 2016; 73(3):268-274. doi: 10.1001/jamapsychiatry.2015.3105

    This cohort study, using a national longitudinal registry, estimates mortality risk of persons with obsessive-compulsive disorder compared with those without this disorder.

  • Prognosis of Brief Psychotic Episodes: A Meta-analysis

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    JAMA Psychiatry. 2016; 73(3):211-220. doi: 10.1001/jamapsychiatry.2015.2313

    This meta-analysis uses 4 operational categories of brief psychotic episodes to look at the risk of recurrence of psychoses after a patient experiences a brief psychotic first episode.

  • Association of Symptom Network Structure With the Course of Depression

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    JAMA Psychiatry. 2015; 72(12) doi: 10.1001/jamapsychiatry.2015.2079

    This study of patients with major depressive disorder reports that a more densely connected symptom network is associated with persistent depression.

  • Incidence of Suicide Among Persons Who Had a Parent Who Died During Their Childhood: A Population-Based Cohort Study

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    JAMA Psychiatry. 2015; 72(12):1227-1234. doi: 10.1001/jamapsychiatry.2015.2094

    This population-based cohort study examines the long-term risks of suicide after parental death.

  • A Telephone-Based Program to Provide Symptom Monitoring Alone vs Symptom Monitoring Plus Care Management for Late-Life Depression and Anxiety: A Randomized Clinical Trial

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    JAMA Psychiatry. 2015; 72(12):1211-1218. doi: 10.1001/jamapsychiatry.2015.2157

    This study compares mental health symptom monitoring alone vs symptom monitoring plus care management among 1018 older, community-dwelling, low-income adults prescribed an antidepressant or anxiolytic and experiencing clinically significant mental health symptoms at intake.

  • Effect of a Cognitive-Behavioral Prevention Program on Depression 6 Years After Implementation Among At-Risk Adolescents: A Randomized Clinical Trial

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    JAMA Psychiatry. 2015; 72(11):1110-1118. doi: 10.1001/jamapsychiatry.2015.1559

    This randomized clinical trial determines whether a cognitive-behavioral prevention program can reduce the incidence of depressive episodes, increase depression-free days, and improve developmental competence 6 years after implementation among at-risk adolescents.

  • Self-blame–Selective Hyperconnectivity Between Anterior Temporal and Subgenual Cortices and Prediction of Recurrent Depressive Episodes

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    JAMA Psychiatry. 2015; 72(11):1119-1126. doi: 10.1001/jamapsychiatry.2015.1813

    Among 75 medication-free patients with remitted major depressive disorder and no relevant comorbidity, this prospective cohort study tests the hypothesis that RSATL-SCSR connectivity for self-blaming relative to other-blaming emotions predicts subsequent recurrence of depressive episodes.

  • Association Between Social Integration and Suicide Among Women in the United States

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    JAMA Psychiatry. 2015; 72(10):987-993. doi: 10.1001/jamapsychiatry.2015.1002

    This study uses data from the Nurses’ Health Study to estimate the association between social integration and suicide.

  • A Longitudinal Study of Resting Heart Rate and Violent Criminality in More Than 700 000 Men

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    JAMA Psychiatry. 2015; 72(10):971-978. doi: 10.1001/jamapsychiatry.2015.1165

    This population epidemiology study of more than 700 000 Swedish men reports that low resting heart rate in late adolescence was associated with an increased risk for violent criminality, nonviolent criminality, exposure to assault, and unintentional injuries in adulthood.

  • Evaluation of Antipsychotic Dose Reduction in Late-Life Schizophrenia: A Prospective Dopamine D 2/3 Receptor Occupancy Study

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    JAMA Psychiatry. 2015; 72(9):927-934. doi: 10.1001/jamapsychiatry.2015.0891

    This study reports on the effects of antipsychotic dose reduction in patients with late-life schizophrenia.

  • Long-Acting Injectable Risperidone for Relapse Prevention and Control of Breakthrough Symptoms After a Recent First Episode of Schizophrenia: A Randomized Clinical Trial

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    JAMA Psychiatry. 2015; 72(8):822-829. doi: 10.1001/jamapsychiatry.2015.0270

    This randomized clinical trial shows that long-acting injectable risperidone resulted in better clinical outcomes than oral risperidone.

  • d -Cycloserine vs Placebo as Adjunct to Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder and Interaction With Antidepressants: A Randomized Clinical Trial

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    JAMA Psychiatry. 2015; 72(7):659-667. doi: 10.1001/jamapsychiatry.2015.0546

    This randomized clinical trial examines whether d-cycloserine augments cognitive behavioral therapy in the treatment of obsessive-compulsive disorder (OCD) and whether concomitant use of antidepressants moderates the effects of d-cycloserine.

  • Risk of Suicide Following Deliberate Self-poisoning

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    JAMA Psychiatry. 2015; 72(6):570-575. doi: 10.1001/jamapsychiatry.2014.3188

    This population-based cohort study finds that a first self-poisoning episode is a strong predictor of subsequent suicide and premature death.

  • Dialectical Behavior Therapy for High Suicide Risk in Individuals With Borderline Personality Disorder: A Randomized Clinical Trial and Component Analysis

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    JAMA Psychiatry. 2015; 72(5):475-482. doi: 10.1001/jamapsychiatry.2014.3039

    This randomized clinical trial reports that a dialectical behavior therapy (DBT) intervention that includes skills training is effective for reducing suicide and self-injury attempts in women with borderline personality disorder (BPD).

  • Posttraumatic Stress Disorder and Incidence of Type 2 Diabetes Mellitus in a Sample of Women: A 22-Year Longitudinal Study

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    JAMA Psychiatry. 2015; 72(3):203-210. doi: 10.1001/jamapsychiatry.2014.2632

    This 22-year longitudinal study reports that women with highest number of symptoms of posttraumatic stress disorder had a nearly 2-fold increased risk of type 2 diabetes mellitus over follow-up than women with no trauma exposure.