This longitudinal cohort study compares rates of self-harm, unintentional injury, and suicide in patients with bipolar disorder prescribed lithium, valproate sodium, olanzapine, or quetiapine fumarate.
This prospective longitudinal study provides evidence that structural abnormalities in anterior insula volume are related to the neurobiology of depressive disorders starting in early childhood.
This longitudinal behavioral and neuroimaging study reports an association between childhood depression and the trajectory of cortical gray matter development in late school-aged children and those in early adolescence.
This case-control cross-sectional study examines memory deficits using functional magnetic resonance imaging in patients with schizophrenia.
This health care use study examines the extent to which incorporating natural language processing of narrative discharge notes improves stratification of risk for death by suicide after medical or surgical hospital discharge.
LaFrance et al evaluate different treatments for psychogenic nonepileptic seizures, including medication only, cognitive behavioral therapy informed psychotherapy only, and cognitive behavioral therapy informed psychotherapy with medication, compared with standard medical care (treatment as usual).
This meta-analysis examines whether behavioral deficits in inhibitory control are associated with shared or disorder-specific structural and functional neural abnormalities in attention-deficit/hyperactivity disorder and obsessive-compulsive disorder.
This national survey describes the limited effectiveness of an abuse-deterrent formulation of OxyContin and residual abuse among patients in drug treatment programs.
This population epidemiology study uses data from the US Centers for Disease Control and Prevention to compare trends and patterns of mortality from self-injury with those from diabetes, influenza and pneumonia, and kidney disease between 1999 and 2014.
This study uses UK national survey data to investigate the association between C-reactive protein levels and risk of suicide.
This randomized clinical trial examines whether the effects of methylphenidate on the dopaminergic system are modified by age and tests the hypothesis that methylphenidate treatment of young but not adult patients with attention-deficit/hyperactivity disorder induces lasting effects.
This Viewpoint suggests that the assertion that prolonged exposure or cognitive processing therapy should be the dominant evidence-based treatments for war-related PTSD is simplistic and may at times be unhelpful or contraindicated.