This Viewpoint reports on the accumulating data indicating that inflammation may play a role in a host of psychiatric illnesses.
This case-control study finds evidence of inflammation of the anterior cingular cortex in major depressive episodes (MDE).
Khandaker et al test the hypothesis that higher serum levels of interleukin 6 and C-reactive protein in childhood would increase future risks for depression and psychosis.
Eraly et al evaluate whether plasma concentration of the inflammatory marker C-reactive protein helps to predict posttraumatic stress disorder symptoms.
Coccaro et al test the hypothesis that plasma inflammatory markers will correlate directly with aggression and will be elevated in individuals with recurrent, problematic, impulsive aggressive behavior.
This meta-analysis supports a proof-of-concept concerning use of anti-inflammatory treatment in depression.
This genome-wide association study assesses genetic loci associated with the lifetime risk for posttraumatic stress disorder in 2 cohorts of US military personnel and veterans.
McGrath et al identify a candidate neuroimaging treatment-specific biomarker that predicts differential outcome to either medication or psychotherapy.
Chiappelli et al investigate whether the level of KYNA changes following psychological stress and whether this change is associated with stress-related behavior. Javitt provides commentary in a related editorial.
This study discusses the association between levels of high-sensitivity C-reactive protein and general psychological distress symptoms.
This study uses UK national survey data to investigate the association between C-reactive protein levels and risk of suicide.