This 2-year observational cohort study investigates whether lower midbrain serotonin transporter binding potential predicts future suicide attempts, intent, and lethality in patients with major depressive disorder.
This Editorial discusses the effectiveness of short-term psychodynamic psychotherapy for major depressive disorder.
This randomized clinical trial explores whether dynamic psychotherapy is not inferior to cognitive therapy in the treatment of major depressive disorder among adults treated in a community mental health center.
This cohort study examines risk for depression in children and grandchildren stratified by biological parents’ and grandparents’ depression status.
This randomized clinical trial tests whether whole-body hyperthermia has specific antidepressant effects when compared with a sham treatment.
This meta-analysis of randomized and observational studies reports comparison of neonatal outcomes among women with untreated antenatal depression vs no depression.
This randomized clinical trial evaluates the safety and efficacy of basimglurant modified-release vs placebo as adjunctive therapy to ongoing antidepressant medication therapy in patients with major depressive disorder who had inadequate response within the current episode.
This randomized trial compares the efficacy of targeted complicated grief treatment, citalopram, both, or neither on the outcomes of patients with complicated grief.
This longitudinal cohort study examines suicide attempt risk factors, methods, and timing among soldiers currently deployed, previously deployed, and never deployed.
This study assesses whether certain factors identified with structural magnetic resonance imaging techniques are able to predict response to electroconvulsive therapy in patients with major depressive disorder.
This randomized clinical trial evaluates the effects of deep brain stimulation in patients with treatment-resistant depression and, in a crossover design, compares active and sham phases for possible detection of placebo effects.
This genome-wide association study assesses analyses from 3 studies of substance use disorder genetics to identify DSM-IV criteria for cannabis dependence in a large African American and European American cohort.
This study uses civil and psychiatric national registers to evaluate patterns and correlates in 10-year trajectories associated with the diagnosis of major depressive disorder in a Danish population.
This study evaluates cortical inhibition as a possible indication of remission of suicidal ideation following magnetic seizure therapy in patients with treatment-resistant depression.
This meta-analysis of observational studies investigates associations between age at menopause, duration of the reproductive period, and depression in postmenopausal women.
This randomized clinical trial compares the efficacy of light treatment, both as monotherapy and in combination with fluoxetine, with a sham placebo condition for adults with nonseasonal major depressive disorder.