This randomized clinical trial assesses the efficacy of sertraline treatment vs placebo in preventing depressive disorders following traumatic brain injury.
This cross-sectional study reports that medication-free patients with major depressive disorder vs bipolar disorder appear to differ in brain activations during emotion regulation, both while depressed and in remission.
National Survey of American Life data were used to examine the interaction of urbanicity and race/ethnicity on lifetime and 12-month major depressive disorder and mood disorder prevalence for African American women and non-Hispanic white women.
This cross-sectional study demonstrates that psychiatric comorbidities are common among individuals with Tourette syndrome and that most comorbidities begin early in life.
This prospective study found that parental history of a suicide attempt conveys a nearly 5-fold increased odds of suicide attempt in offspring at risk for mood disorder.
This retrospective quantification and assessment of temporal patterns of DSM-IV diagnoses not otherwise specified among youth finds that subthreshold diagnoses have expanded, a trend that will continue in the DSM-5 era.
Singh and coauthors examine anomalous neural processing of reward in children at familial risk for bipolar disorder.
Kotov et al examine the associations between symptom course and long-term outcome to identify natural boundaries within psychotic disorders. Kendler provides an editorial.
Castrén describes the network hypothesis of antidepressant action that proposes that
recovery from depression and related mood disorders is a gradual process that develops slowly and is
facilitated by structured guidance and rehabilitation.
Benros and coauthors estimate the effect of autoimmune diseases and infections on the risk of developing mood disorders.
Crum et al used data from the National Epidemiologic Survey on Alcohol and Related Conditions to evaluate the hypothesis that alcohol self-medication of mood symptoms increases the probability of subsequent onset and the persistence or chronicity of alcohol dependence.