This cohort study investigates associations between striatal activity (measured via functional magnetic resonance imaging) during reward anticipation and weight change induced by amisulpride, a selective dopamine D2 receptor antagonist, among antipsychotic-naive patients with schizophrenia.
This 22-year longitudinal study reports that women with highest number of symptoms of posttraumatic stress disorder had a nearly 2-fold increased risk of type 2 diabetes mellitus over follow-up than women with no trauma exposure.
This study assesses cardiometabolic risk in patients with first-episode schizophrenia spectrum disorders.
This case control study suggests that oleoylethanolamide-mediated signaling plays an important role for hedonic regulation of food-craving and obesity in humans and, thus, may be a valuable target for developing novel antiobesity drugs.
This cross-sectional analysis using the Nurses’ Health Study II cohort reports that posttraumatic stress disorder symptoms are associated with increased food addiction prevalence. Strategies aimed at reducing obesity associated with posttraumatic stress disorder may require psychological and behavioral interventions that address dependence on food and/or use of food to cope with distress.
Lasserre and colleagues aimed to determine whether the subtypes of major depressive disorder (MDD; melancholic, atypical, combined, or unspecified) are predictive of adiposity in terms of the incidence of obesity and changes in body mass index (calculated as weight in kilograms divided by height in meters squared), waist circumference, and fat mass.
Using the age at onset of posttraumatic stress disorder (PTSD) symptoms, Kubzansky et al investigate whether women who develop PTSD are more likely than trauma-exposed women without PTSD or those with no trauma or PTSD symptoms to gain weight.
Choong et al for the ODEX team determine whether polymorphisms within CRTC1 are associated with adiposity markers in psychiatric patients and the general population.