This population-based cohort study examines the association of perinatal risk factors with subsequent development of obsessive-compulsive disorder in Sweden.
This article analyzes the mechanisms of harm-avoidance learning as a potential model for obsessive-compulsive disorder.
This meta-analysis examines whether behavioral deficits in inhibitory control are associated with shared or disorder-specific structural and functional neural abnormalities in attention-deficit/hyperactivity disorder and obsessive-compulsive disorder.
This randomized clinical trial examines the relative efficacy of weight-adjusted d-cycloserine (25 or 50 mg) vs placebo augmentation of cognitive behavior therapy for youth with obsessive-compulsive disorder and assesses if concomitant antidepressant medication moderated effects.
This randomized clinical trial evaluates the use of N-acetylcysteine in short-term treatment of skin-picking disorder.
This cohort study, using a national longitudinal registry, estimates mortality risk of persons with obsessive-compulsive disorder compared with those without this disorder.
This randomized clinical trial examines whether d-cycloserine augments cognitive behavioral therapy in the treatment of obsessive-compulsive disorder (OCD) and whether concomitant use of antidepressants moderates the effects of d-cycloserine.
This meta-analysis shows that various reporting biases are present for trials on the efficacy of US Food and Drug Administration–approved second-generation antidepressants for anxiety disorders.
This population-based study of national health registries in Denmark finds that Tourette syndrome/chronic tic disorder (TS/CT) and obsessive-compulsive disorder (OCD) cluster in families, with a higher familial aggregation for TS/CT.
This cross-sectional study demonstrates that psychiatric comorbidities are common among individuals with Tourette syndrome and that most comorbidities begin early in life.
This latent class analysis of obsessive-compulsive (OC) features, cross-sectional tests of association, and classic twin genetic analysis finds phenotypic and genetic overlap between OC and pathological gambling.
This retrospective analysis describes features of anterior cingulate cortex structure and connectivity that predict clinical response to dorsal anterior cingulotomy for treatment of refractory obsessive-compulsive disorder. See also the editorial by van den Heuvel.
Meier et al assessed whether patients with obsessive-compulsive disorder (OCD) experience an enhanced risk of developing schizophrenia and schizophrenia spectrum disorders and whether a family history of OCD constitutes a risk factor for schizophrenia and schizophrenia spectrum disorders.
This randomized trial suggests that the type of family therapy matters in the treatment of adolescent-onset anorexia nervosa.
Lopes and colleagues aimed to determine the efficacy and safety of gamma ventral capsulotomy for intractable obsessive-compulsive disorder (OCD) in a double-blind, placebo-controlled, randomized clinical trial.
In a 14-week randomized clinical trial, Freeman and coauthors examine the relative efficacy of family-based cognitive behavior therapy involving exposure plus response prevention vs a family-based relaxation treatment control condition for children 5 to 8 years of age.