In an observational, longitudinal study, Judd and coauthors determine the prevalence of overtly expressed irritability/anger and its effect on intake presentation and the long-term course of illness.
This randomized trial compares the efficacy of targeted complicated grief treatment, citalopram, both, or neither on the outcomes of patients with complicated grief.
This study investigates childhood risk factors and functioning in young adults with persistent, remitted, and late-onset ADHD.
This randomized clinical trial evaluates the safety and efficacy of basimglurant modified-release vs placebo as adjunctive therapy to ongoing antidepressant medication therapy in patients with major depressive disorder who had inadequate response within the current episode.
This study determines whether an Internet-assisted intervention using whole-population screening that targets the most symptomatic 4-year-old children is effective at 6 and 12 months after the start of treatment.
This multisite, randomized clinical trial finds that venlafaxine XR was well tolerated by most patients and an effective antidepressant for decreasing core symptoms of depression and improving spinal cord injury–related disability.
Singh and coauthors examine anomalous neural processing of reward in children at familial risk for bipolar disorder.
This randomized clinical trial examines the effects of telephone-delivered cognitive-behavioral therapy compared with telephone-delivered nondirective supportive therapy in rural older adults with generalized anxiety disorder.
This randomized clinical trial reports that problem adaptation therapy was more efficacious than supportive therapy for cognitively impaired patients in reducing depression and disability. Problem adaptation therapy may provide relief to a large group of depressed and cognitively impaired older adults with few treatment options.
Kühn and Gallinat determine whether frequent pornography consumption is associated with the frontostriatal network.
In a 14-week randomized clinical trial, Freeman and coauthors examine the relative efficacy of family-based cognitive behavior therapy involving exposure plus response prevention vs a family-based relaxation treatment control condition for children 5 to 8 years of age.