This 2-year observational cohort study investigates whether lower midbrain serotonin transporter binding potential predicts future suicide attempts, intent, and lethality in patients with major depressive disorder.
This meta-analysis examines whether behavioral deficits in inhibitory control are associated with shared or disorder-specific structural and functional neural abnormalities in attention-deficit/hyperactivity disorder and obsessive-compulsive disorder.
This case-control cross-sectional study examines memory deficits using functional magnetic resonance imaging in patients with schizophrenia.
This case-control study used whole-brain thalamic functional connectivity maps to examine the association of thalamic dysconnectivity and conversion to psychosis in youth and young adults at elevated clinical risk.
This fMRI study determines differences in brain responses, habituation, and connectivity during exposure to mildly aversive sensory stimuli in youth with autism spectrum disorders (ASDs) and sensory overresponsivity (SOR) compared with youth with ASDs without SOR and control subjects.
This cross-sectional study reports that medication-free patients with major depressive disorder vs bipolar disorder appear to differ in brain activations during emotion regulation, both while depressed and in remission.
This case-control study finds that cocaine addiction is associated with disturbed resting-state functional connectivity in several specific striatal-cortical circuits.
This study suggests that hemispheric specialization could serve as a potential imaging biomarker of schizophrenia.
This positron emission tomographic functional magnetic resonance imaging study found in vivo evidence for a deficit in the capacity for dopamine release in the dorsolateral prefrontal cortex in schizophrenia.
This case-control cross-sectional study finds that short-term treatment with antipsychotics was associated with prefrontal cortical thinning, but that treatment was associated with better cognitive control and increased prefrontal functional activity.
This Viewpoint discusses the effect of the exposure of children to violence. A deeper understanding of the different perspectives on the intergenerational effect of war is central to the work of health care professionals around the world.
This cross-sectional study of positron emission tomography (PET) findings of brainstem raphe binding of serotonin1A in suicide attempters relates the severity of suicidal ideation to brainstem and prefrontal serotonin1A binding potential.
This study assesses dendritic spine loss in the dorsolateral prefrontal cortex in individuals with schizophrenia and individuals with bipolar disorder and suggests that the 2 disorders may share some common pathophysiological features.
Hauser et al determine the impaired decision-making and learning mechanisms in adolescents with attention-deficit/hyperactivity disorder using advanced computational models, as well as the related neural reward prediction error processes using multimodal neuroimaging.
Kohno and colleagues aimed to determine how methamphetamine-dependent and control participants differed in brain activation during a risky decision-making task, resting-state functional connectivity within mesolimbic and executive control circuits, and the relationships between these measures.
Kühn and Gallinat determine whether frequent pornography consumption is associated with the frontostriatal network.
Lerman et al examine alterations underlying nicotine dependence with the hypothesis that the salience, executive control, and default mode networks will reflect nicotine withdrawal and predict abstinence-induced craving and cognitive defects. See also the editorial by London and Ghahremani.