This meta-analysis uses 4 operational categories of brief psychotic episodes to look at the risk of recurrence of psychoses after a patient experiences a brief psychotic first episode.
This study of patients with major depressive disorder reports that a more densely connected symptom network is associated with persistent depression.
This Viewpoint opposes adoption of the Research Domain Criteria (RDoC) initiative to replace categorical with dimensional diagnoses.
This Viewpoint supports adoption of the Research Domain Criteria (RDoC) initiative to replace categorical with dimensional diagnoses.
This population epidemiology study tests whether childhood psychiatric health problems adversely affect adult functioning even if the problems themselves do not persist.
This population-based, case-control study investigates white matter differences using diffusion-weighted imaging (whole-brain tractography) in adolescents who report psychotic experiences.
To examine the direct and indirect relationships between perceived racial discrimination and common forms of psychopathology, 12 common diagnoses were assessed in a nationally representative sample of African American and Afro-Caribbean adults.
This meta-analysis identified a concordance across psychiatric diagnoses in terms of integrity of an anterior insula/dorsal anterior cingulate–based network, which may relate to executive function deficits observed across diagnoses.
This cross-sectional study reports that κ-opioid receptor availability in an amygdala–anterior cingulate cortex–ventral striatal neural circuit mediates the phenotypic expression of trauma-related loss (ie, dysphoria) symptoms and that an activated corticotropin-releasing factor/hypothalamic-pituitary-adrenal axis system may indirectly mediate this association.
Lahey et al test predictions derived from a hierarchical-dimensional model of psychopathology that (1) heterotypic continuity is widespread, even controlling for homotypic continuity, and that (2) the relative magnitudes of heterotypic continuities recapitulate the relative magnitudes of cross-sectional correlations among diagnoses at baseline.
Kelleher et al assessed psychotic symptoms (attenuated or frank) as a clinical marker of risk for
Weisz et al conduct a meta-analysis of 52 randomized trials directly comparing evidence-based
psychotherapies with usual clinical care for psychopathology in children and adolescents. See also
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