This longitudinal study examines the association of long-term marijuana use in young adults with the response of the nucleus accumbens to award anticipation.
This cross-sectional study examines whether common risk variants for psychosis are associated with individual variation in the ventral striatum.
This cohort study investigates associations between striatal activity (measured via functional magnetic resonance imaging) during reward anticipation and weight change induced by amisulpride, a selective dopamine D2 receptor antagonist, among antipsychotic-naive patients with schizophrenia.
This meta-analysis of functional magnetic resonance imaging studies assessed the differences between patients with schizophrenia spectrum disorders and healthy controls in ventral striatal activation during reward processing.
This experimental study in humans and rats reports that organisms have diminished ability to modulate behavior as a function of reward during withdrawal of nicotine.
Singh and coauthors examine anomalous neural processing of reward in children at familial risk for bipolar disorder.
Hauser et al determine the impaired decision-making and learning mechanisms in adolescents with attention-deficit/hyperactivity disorder using advanced computational models, as well as the related neural reward prediction error processes using multimodal neuroimaging.
Kühn and Gallinat determine whether frequent pornography consumption is associated with the frontostriatal network.
In an examination of a well-established monetary reward anticipation paradigm during functional magnetic resonance imaging, Grimm and coauthors examined a large sample of healthy first-degree relatives of schizophrenic patients and compared their neural responses to reward anticipation with those of carefully matched controls without a family psychiatric history. See the editorial by Abi-Dargham.
Bebko et al identify neuroimaging measures that are associated with behavioral and emotional dysregulation pathologic dimensions in a multisite cohort of youth. Leibenluft provides an invited commentary
Dombrovski et al describe the neural circuit abnormalities that underlie disadvantageous choices in depressed patients at risk for suicide and relate these abnormalities to impulsivity, which is one of the components of vulnerability to suicide.
Müller et al assess whether adolescents with prenatal exposure to maternal cigarette smoking differ from their nonexposed peers in the response of the ventral striatum to the anticipation or the receipt of a reward.