This genetic analysis examines whether neuronal activity-dependent changes of gene expression are dysregulated in schizophrenia.
This meta-analysis describes studies reporting on the presence of 40-Hz auditory steady-state response impairments in patients with schizophrenia and examines the effects of participant group, stimulus parameters, and analysis and recording techniques.
This Special Communication examines the degree to which modern operationalized diagnostic criteria for schizophrenia reflect the main clinical features of the disorder as described historically by diagnostic experts.
This longitudinal cohort study uses data from the National Medicaid Analytic Extract and the National Center for Health Statistics to assess the postdischarge risk for suicide among psychiatric inpatients.
This randomized clinical trial compares the effects of adjunctive raloxifene with antipsychotic therapy vs antipsychotics alone on illness severity in women with refractory schizophrenia.
This cross-sectional study examines associations between copy number variants associated with intellectual disability and schizophrenia in a search for novel schizophrenia risk loci.
This case-control study examines whether the pattern of brain connectivity across striatal subregions is abnormal in unmedicated patients with schizophrenia and whether this abnormality relates to psychotic symptoms and extrastriatal dopaminergic transmission.
This study uses Swedish national registry data to identify triggers for violent behavior in patients with schizophrenia spectrum and bipolar disorders, and to compare risk in those populations vs healthy controls.
This article discusses advances in the study of corticostriatal circuits and the involvement of these circuits in psychiatric disorders such as schizophrenia.
This cross-sectional study examines whether common risk variants for psychosis are associated with individual variation in the ventral striatum.
This meta-analysis evaluates the levels of glutamate, glutamine, or the combined Glx signals determined with proton magnetic resonance spectroscopy in patients at high risk for schizophrenia as well as in those with first-episode psychosis or chronic schizophrenia.
This study identifies a potential systems-level intermediate phenotype linked to emotion processing in schizophrenia and examines the psychological association, task specificity, test-retest reliability, and clinical validity of the identified phenotype.
This exome sequencing study of family members with bipolar disorder from 8 multiplex families tested rare, segregating variants in 3 independent samples, followed by association testing in a large case-control meta-analysis.