This population-based longitudinal study investigates the association of circulating levels of vitamin B12, folate, and sulfur amino acids with the rate of total brain volume loss and the change in white matter hyperintensity volume in older adults.
Du et al investigate cerebral bioenergetics in schizophrenia via measurement of creatine kinase activity using in vivo 31P magnetization transfer spectroscopy in a cross-sectional case-control study of 26 cases and 26 controls. The primary outcome measure was the forward rate constant of the creatine kinase enzyme in the frontal lobe.
This Neuroscience and Psychiatry article proposes that changing levels of estradiol may directly modify the activity of dorsal and ventral emotional regulation nodes and circuits, modifying the cognitive and emotional consequences of life stress and leading to depression in women.
This genome-wide association analysis identifies a novel locus for neuroticism and shows polygenic association with major depressive disorder (MDD).
This case-control study finds evidence of inflammation of the anterior cingular cortex in major depressive episodes (MDE).
Bustillo et al examine glutamine, glutamate, and glutamine to glutamate ratio in the dorsal anterior cingulate, as well as their relationships with symptoms and cognition in schizophrenia.