Submitted for Publication: January 19, 2011; final revision received July 18, 2011; accepted July 21, 2011.
Financial Disclosure: Dr Arango has been a consultant to or has received honoraria from AstraZeneca, Bristol-Myers Squibb, Janssen-Cilag, Lundbeck, Otsuka, Pfizer, Roche, Servier, and Schering-Plough. Dr Castro-Fornieles has been a consultant to Lilly. Dr C. Moreno has served as a consultant to AstraZeneca, Otsuka, and Bristol-Myers Squibb. Dr Parellada has received travel support from AstraZeneca and Juste. Dr González-Pinto is employed by the University of the Basque Country and has been a consultant for the Ministry of Science of Spain and the Basque Government. Dr González-Pinto also gives conferences, acts as consultant to, or receives grants from Lilly, Janssen, MSD, Lundbek, AstraZeneca, Almirall, sanofi-aventis, BMS, Novartis, and Pfizer. The rest of the authors declare no conflicts of interest.
Funding/Support: This study was supported by the Spanish Ministry of Health and Social Policy, Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Red Temática de Investigación Cooperative Sanitaria RD06/0011 (Red de Enfermedades Mentales y Trastornos Afectivos y Psicóticos Network), Fundación Alicia Koplowitz, and by grants PI02/1248, PI05/0678, and G03/032 from the Spanish Ministry of Health and Social Policy, Institute of Health Carlos III (Madrid, Spain), Centro para el Desarrollo Tecnológico e Industrial (CDTI) under the Consorcios Estratégicos Nacionales en Investigación Técnica (CENIT) programme Advanced Molecular Imaging Technologies (AMIT) project and supported by the Spanish Ministry of Science and Innovation.
Previous Presentations: Presented as a poster at the 12th International Congress of Schizophrenia Research; March 31, 2009; San Diego, California. The abstract was published in Schizophrenia Bulletin (2009;35[suppl 1]:219) and was presented as a poster at the Second Biennial Schizophrenia International Research Conference; April 12, 2010; Florence, Italy. The abstract was published in Schizophrenia Research (10.1016/j.schres.2010.02.605) and presented at the 57th Annual Meeting of the American Academy of Child and Adolescent Psychiatry; October 28, 2010; New York, New York; and published in The Scientific Proceedings of the 2010 Annual Meeting of the American Academy of Child and Adolescent Psychiatry (2010;37:247).
Additional Contributions: Jose de Arriba, MSc, of the Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Marañón, and Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain, provided data management.