Submitted for Publication: April 10, 2012; final revision received June 27, 2012; accepted July 5, 2012.
Published Online: September 3, 2012. doi:10.1001/2013.jamapsychiatry.5
Author Contributions: Drs Doehrmann and Ghosh contributed equally to this article and confirm that they had full access to all of the data in the study, performed the statistical analyses for this article, and take responsibility for the integrity of the data and the accuracy of the data analysis.
Financial Disclosure: Dr Doehrmann was supported by postdoctoral fellowship DO-1469/1-1 from the Deutsche Forschungsgemeinschaft. Neuroimaging was supported by the Poitras Center for Affective Disorders Research. Dr Hofmann is a paid consultant for Merck/Schering-Plough and is supported by National Institutes of Mental Health grant MH078308. Dr Pollack is supported by National Institutes of Mental Health grant MH075889. He additionally is a member of the advisory boards or a consultant for BrainCells, Eli Lilly, Johnson & Johnson, MedAvante, Labopharm, Mindsite, Otsuka, Targia Pharmaceuticals, and Pfizer. He has received research grants from Bristol-Myers Squibb, Euthymics, Forest Laboratories, GlaxoSmithKline, Eli Lilly, National Center for Complementary and Alternative Medicine, National Institute on Drug Abuse, and National Institutes of Mental Health. Continuing Medical Education–supported activities of Dr Pollack were sponsored by AstraZeneca, Sepracor, and Pfizer. He holds equity in MedAvante, Mensante Corporation, Mindsite, and Targia Pharmaceuticals and receives royalties for SIGH-A, SAFER interviews.
Previous Presentations: Parts of the data from this article were presented at the 44th Annual Convention of the Association for Behavioral and Cognitive Therapy; November 20, 2010; San Francisco, California; the 2011 Annual Conference of the Anxiety Disorders Association of America; March 26, 2011; New Orleans, Louisiana; and the 17th Annual Meeting of the Organization for Human Brain Mapping; June 26, 2011; Quebec City, Quebec, Canada.
Additional Information: Data were collected from a subsample of subjects who took part in a clinical trial registered at clinicaltrials.gov (NCT00515879). However, the present article does not report findings from this clinical trial.
Additional Contributions: We gratefully acknowledge the Athinoula A. Martinos Imaging Center at McGovern Institute for Brain Research for providing an excellent neuroimaging environment.