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Letters to the Editor |

Inappropriate Data and Measures Lead to Questionable Conclusions—Reply

Robert D. Gibbons, PhD; C. Hendricks Brown, PhD; Kwan Hur, PhD; John M. Davis, MD; J. John Mann, MD
JAMA Psychiatry. 2013;70(1):121-123. doi:10.1001/jamapsychiatry.2013.749.
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We appreciate Spielmans and colleagues' interest in our article; however, their concerns about the data in our article are unfounded.

Spielmans and colleagues state that study LYAQ included atomoxetine as a treatment and should have been excluded. In fact, the first 2 active treatment visits did not include atomoxetine and our analysis of the data from this study was restricted to this period (days 1-42 postbaseline depending on the subject). Furthermore, although patients in this study had comorbidities including attention-deficit/hyperactivity disorder, the majority (81%) of patients had a depressive disorder. As such, our inclusion of this study was scientifically appropriate.

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Correspondence

January 1, 2013
Glen I. Spielmans, PhD; Jon Jureidini, PhD, MBBS, FRANZCP; David Healy, MD; Robert Purssey, MBBS, FRANZCP
JAMA Psychiatry. 2013;70(1):121-123. doi:10.1001/jamapsychiatry.2013.747.
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