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In This Issue of JAMA Psychiatry |

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JAMA Psychiatry. 2013;70(8):769-771. doi:10.1001/jamapsychiatry.2013.1997.
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Within the human brain, a system of long-distance pathways, referred to as the “rich club,” has been proposed to play an important role in enabling efficient communication between distant parts of the neural network. In their study, van den Heuvel and colleagues show that schizophrenia involves a reduced connectivity of this centrally embedded communication backbone and that abnormal wiring of the brain’s rich club may contribute to altered brain dynamics and reduced integration of information between subsystems of the brain in patients.

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