Submitted for Publication: July 12, 2013; final revision received November 2, 2013; accepted December 4, 2013.
Published Online: April 16, 2014. doi:10.1001/jamapsychiatry.2014.35.
Study concept and design: Akdeniz, Tost, Streit, Schäfer, Rietschel, Kirsch, Meyer-Lindenberg.
Acquisition, analysis, or interpretation of data: Akdeniz, Tost, Streit, Haddad, Wüst, Schäfer, Schneider, Kirsch, Meyer-Lindenberg.
Drafting of the manuscript: Akdeniz, Tost, Meyer-Lindenberg.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Akdeniz, Tost, Streit, Schäfer, Schneider.
Obtained funding: Meyer-Lindenberg.
Administrative, technical, or material support: Akdeniz, Tost, Haddad, Wüst, Schäfer, Schneider, Rietschel, Meyer-Lindenberg.
Study supervision: Tost, Rietschel, Kirsch, Meyer-Lindenberg.
Conflict of Interest Disclosures: Dr Meyer-Lindenberg has received consultant fees and travel expenses from Alexza Pharmaceuticals, AstraZeneca, Bristol-Myers Squibb, Defined Health, Decision Resources, Desitin Arzneimittel, Elsevier, F. Hoffmann–La Roche, Gerson Lehrman Group, Grupo Ferrer, Les Laboratoires Servier, Lilly Deutschland, Lundbeck Foundation, Outcome Sciences, Outcome Europe, PriceSpective, and Roche Pharma and has received speaker’s fees from Abbott, AstraZeneca, BASF, Bristol-Myers Squibb, GlaxoSmithKline, Janssen-Cilag, Lundbeck, Pfizer Pharma, and Servier Deutschland. No other disclosures were reported.
Funding/Support: This work was supported by grant HEALTH-F2-2010-241909 (Project EU-GEI) from the European Community’s Seventh Framework Programme. Dr Tost is supported by grant 01GQ1102 from the German Federal Ministry of Education and Research.
Role of the Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: John McGrath, MD, PhD, Queensland Brain Institute, University of Queensland, Queensland, Australia, provided valuable comments on the manuscript, and Dagmar Gass, Hasan Elkin, MD, Edda Bilek, MSc, Oliver Grimm, MD, Emanuel Schwarz, PhD, Andreas Böhringer, MD, PhD, Christine Niemeyer, MSc, Carolin Mössnang, PhD, Janina Schweiger, MD, Tobias Gradinger, BSc, Jasmin Buchholz, BSc, Lena Geiger, MSc, and Valerie Eidam, Central Institute of Mental Health, Mannheim, Germany, provided research assistance during data collection. We thank all individuals who have supported our work by participating in these studies. No compensation was received from the funders for these contributions.
Correction: This article was corrected online June 20, 2014, for a typographical error in the Methods section.