Submitted for Publication: November 25, 2013; final revision received April 22, 2014; accepted April 27, 2014.
Published Online: August 13, 2014. doi:10.1001/jamapsychiatry.2014.1087.
Study concept and design: Cullen, Klimes-Dougan, Mueller, Lim.
Acquisition, analysis, or interpretation of data: Cullen, Klimes-Dougan, Westlund, Mueller, Houri, Eberly.
Drafting of the manuscript: Cullen, Klimes-Dougan, Westlund, Lim.
Critical revision of the manuscript for important intellectual content: Cullen, Klimes-Dougan, Westlund, Mueller, Houri, Eberly.
Statistical analysis: Cullen, Westlund, Houri, Eberly.
Obtained funding: Cullen.
Administrative, technical, or material support: Cullen, Klimes-Dougan, Mueller.
Study supervision: Cullen, Klimes-Dougan.
Conflict of Interest Disclosures: None reported.
Funding/Support: The study was funded by National Institute of Mental Health grant K23MH090421 (Dr Cullen) and Biotechnology Research Center grant P41 RR008079 (Center for Magnetic Resonance Research), the National Alliance for Research on Schizophrenia and Depression, the University of Minnesota Graduate School, and the Minnesota Medical Foundation. This work was carried out in part using computing resources at the University of Minnesota Supercomputing Institute.
Role of the Sponsor: The funding sources supported the roles of design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation of the manuscript. The funding sources were not involved in the decision to submit the manuscript for publication.
Additional Contributions: We first and foremost thank the patients and families who contributed to this study.