Submitted for Publication: February 4, 2014; final revision received April 7, 2014; accepted May 21, 2014.
Published Online: September 17, 2014. doi:10.1001/jamapsychiatry.2014.1221.
Study concept and design: Pietrzak, Huang, Neumeister.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Pietrzak, Naganawa, Huang, Corsi-Travali, Zheng, Lim, Neumeister.
Critical revision of the manuscript for important intellectual content: Pietrzak, Huang, Stein, Henry, Ropchan, Lin, Carson, Neumeister.
Statistical analysis: Pietrzak, Carson.
Obtained funding: Huang, Neumeister.
Administrative, technical, or material support: Pietrzak, Huang, Corsi-Travali, Zheng, Henry, Lim, Ropchan, Lin, Neumeister.
Study supervision: Ropchan, Carson, Neumeister.
Conflict of Interest Disclosures: None reported.
Funding/Support: This project was supported by the National Institutes of Health (NIH) through the following grants: R21MH096105, R21MH085627, RO1MH096876, and RO1MH102566. This was also supported by Clinical and Translational Science Award grant UL1 RR024139 from the National Center for Research Resources and the National Center for Advancing Translational Science, components of the NIH, NIH Roadmap for Medical Research, and Clinical Neurosciences Division of the US Department of Veterans Affairs National Center for Posttraumatic Stress Disorder. We acknowledge grant support from Eli Lilly Inc for support in the development of [11C]LY2795050.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: The content of this article is solely the responsibility of the authors and does not necessarily represent the official view of the NIH or VA.
Additional Contributions: We acknowledge the work of the staff of the Yale PET Center and the nursing support from Brenda Breault, RN, BSN, Cynthia D’Amico, RN, BSN, Michelle San Pedro, RN, CCRC, Jamie Cyr, RN, CCRN, and Deborah Campbell, RN, for their contributions with patient care during the positron emission tomographic scans. They did not receive compensation from a funding sponsor for their contributions.
Correction: The article was corrected online September 24, 2014, for an error in the Results section and Table 1, missing information in the Methods section, and an error in Figure 2.