Catherine Judd, PA-C, MS, Steven Krebaum, MS, Melinda Down, PhD, Larry Alder, PA, Monica Basco, PhD, Jeanette Doyle, MA, Charlene McSwain, BSN, Jeanne Nash, RN, and Mustafa Husain, MD, provided clinical research support. Gratitude is expressed to the cadre of cognitive therapists at The University of Texas Southwestern Medical Center, Dallas, including G. Gregory Eaves, PhD, Paul Silver, PhD, and Rodger Kobes, MD, PhD. Julie Lowe, BA, Joe Webster, BS, Brad Witte, BS, Monica Lopez, BS, Dennis Strickland, RPh, and Joe Alcorn, RPh, provided research support. Michelle White, BS, Edna Christian, MA, and Sheria Oswalt, BA, assisted with manuscript preparation. Paul J. Orsulak, PhD, supervised monoamine oxidase assays. Brian F. Shaw, PhD, provided consultation and rated cognitive therapy. Janet Smith, MS, Qin-chang Cheng, PhD, and Janaki Ramanan, PhD, provided programming support, and Barbara Foster, PhD, gave statistical support. Armand Loranger, PhD, and Jonathon W. Stewart, MD, provided consultation on this research. A. John Rush, MD (Betty Jo Hay Distinguished Chair in Mental Health and Rosewood Corporation Chair in Biomedical Science) gave advice. Myron Weiner, MD (professor and vice chairman for clinical services, Aradine S. Ard Chair in Brain Science, and Dorothy L. and John P. Harbin Chair in Alzheimer's Disease Research) commented on an earlier draft of this report. We also acknowledge the careful and thoughtful comments of the anonymous reviewers. Kenneth Z. Altshuler, MD (Stanton Sharp Professor and Chairman) provided administrative support.