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Can Sublingual Testosterone Increase Subjective and Physiological Measures of Laboratory-Induced Sexual Arousal?

Adriaan Tuiten, PhD; Jack van Honk, PhD; Rien Verbaten, PhD; Ellen Laan, PhD; Walter Everaerd, PhD; Henderikus Stam, PhD
Arch Gen Psychiatry. 2002;59(5):465-466. doi:10.1001/archpsyc.59.5.465.
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Recently1 we demonstrated a delay in effect of sublingual testosterone on both physiological and subjective sexual arousal in women. The delay for these effects was approximately 4 hours. We suggested that under the condition of testosterone administration, there were increases in physiological sexual responding during successive measures, and that the increase in subjective sexual excitement resulted from a heightened awareness of these alterations in genital arousal.

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Comparison between experiment 1 (N = 8) and the present study (experiment 2, N = 10) for the average relative increases in vaginal pulse amplitude (VPA) induced by an erotic film fragment viewed 4.5 hours after sublingual placebo and testosterone intake (A). Comparison between both experiments for the mean scores of experiences of "sexual lust" (B) and "genital sensations" (C) after exposure to these erotic film excerpts.

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