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Comment & Response |

Abuse-Deterrent Formulations of Prescription Opioids

Xiulu Ruan, MD1; Srinivas Chiravuri, MD2; Alan D. Kaye, MD, Ph.D1
[+] Author Affiliations
1Department of Anesthesia, Louisiana State University Health Science Center, New Orleans
2Department of Anesthesiology, University of Michigan Health System, Ann Arbor
JAMA Psychiatry. 2015;72(8):849-850. doi:10.1001/jamapsychiatry.2015.0721.
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To the Editor It is with interest that we read the article “Abuse-Deterrent Formulations and the Prescription Opioid Abuse Epidemic in the United States: Lessons Learned From OxyContin” published in JAMA Psychiatry.1 Through their survey study, Cicero and Ellis1 concluded that abuse-deterrent formulations (ADFs) can have the intended purpose of curtailing abuse, but only with limited effectiveness, and efforts to reduce opioid supply alone with ADF technology will not mitigate the opioid abuse program in the United States.

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May 1, 2015
Theodore J. Cicero, PhD; Matthew S. Ellis, MPE
1Department of Psychiatry, Washington University, St Louis, Missouri
JAMA Psychiatry. 2015;72(5):424-430. doi:10.1001/jamapsychiatry.2014.3043.
August 1, 2015
Richard C. Dart, MD, PhD; S. Geoff Severtson, PhD; Jody L. Green, PhD
1RADARS System, Denver Health and Hospital Authority, Denver, Colorado
JAMA Psychiatry. 2015;72(8):849. doi:10.1001/jamapsychiatry.2015.0723.
August 1, 2015
Theodore J. Cicero, PhD; Matthew S. Ellis, MPE
1Department of Psychiatry, Washington University in St Louis, St Louis, Missouri
JAMA Psychiatry. 2015;72(8):850-851. doi:10.1001/jamapsychiatry.2015.0674.
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