We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Neuroscience and Psychiatry |

Relational Memory as a Possible Neurocognitive Marker of Schizophrenia

Martin Lepage, PhD1,2,3; Colin Hawco, PhD4; Michael Bodnar, PhD2,3
[+] Author Affiliations
1Department of Psychiatry, McGill University, Montreal, Quebec, Canada
2Department of Psychology, McGill University, Montreal, Quebec, Canada
3Douglas Mental Health University Institute, Montreal, Quebec, Canada
4Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
JAMA Psychiatry. 2015;72(9):946-947. doi:10.1001/jamapsychiatry.2015.0488.
Text Size: A A A
Published online


This Neuroscience and Psychiatry article discusses the implications of relational memory deficits in schizophrenia and whether they are a reliable cognitive marker for the disease.

Long-term or episodic memory can be understood along several dimensions, including verbal vs abstract, spatial vs nonspatial, and item vs relational memory. The latter has represented a field of growing interest over the past 15 years, particularly in cognitive neuroscience and neuroimaging. In basic terms, item memory is a metric related to a single piece of information, whereas relational memory involves forming a relationship between 2 or more pieces of information. Relational memory can occur within many contexts such as linking multiple objects together (eg, “I saw x with y.”) or within a spatial or temporal context (eg, “I saw x at the park in the afternoon.”). However, relational memory cannot be considered successful in the absence of item memory (eg, “I saw someone at the park.”). Relational memory requires more elaborate processing to create associations that can later be recalled together. By consequence, memory performance for individual items can be improved with deep semantic encoding (eg, combining items into groups) as opposed to shallow encoding (eg, remembering items individually). Not surprisingly, forming relationships between items is easiest when items share semantic features such as category (eg, hammer and screwdriver are tools).

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles