Physicians are at high risk for suicide, particularly during internship, with suicidal ideation increasing 4-fold. Guille and colleagues conduct a randomized clinical trial of web-based cognitive behavioral therapy (wCBT) in 199 interns from multiple specialties. During at least 1 point in the internship, 12% of interns in the wCBT group and 21.2% of interns in the control group endorsed suicidal ideation. The relative risk to endorse suicidal ideation in the wCBT group was 0.40. In an editorial, Reynolds reviews the importance of addressing mental health needs in training physicians.