We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

How Similar Are the Disorders Included Under the Umbrella of Obsessive-Compulsive Disorder and Related Disorders?

Daniel L. C. Costa, MD1; Juliana Belo Diniz, MD, PhD1; Eurípedes Constantino Miguel, MD, PhD1
[+] Author Affiliations
1Department and Institute of Psychiatry, University of Sao Paulo Medical School, Sao Paulo, Brazil
JAMA Psychiatry. 2016;73(8):877. doi:10.1001/jamapsychiatry.2016.1342.
Text Size: A A A
Published online


To the Editor In JAMA Psychiatry, Grant and colleagues1 demonstrated the efficacy of N-acetylcysteine (NAC) in the treatment of excoriation disorder (ED). The same group had previously reported the benefits of NAC for adults with trichotillomania (TTM).2 In both studies, NAC was used in monotherapy in otherwise treatment-free patients. In the DSM-5, ED and TTM were included under the umbrella of obsessive-compulsive disorder (OCD) and related disorders because of similarities regarding phenotypic expression and common putative neurobiological underpinnings between these disorders and OCD. When used for treatment-resistant OCD, NAC was not more effective than placebo as a selective serotonin reuptake inhibitor (SSRI) augmentation strategy.3


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





August 1, 2016
Eric W. Leppink, BA; Samuel R. Chamberlain, MD, PhD; Jon E. Grant, JD, MD, MPH
1Department of Psychiatry and Behavioral Neuroscience, Pritzker School of Medicine, University of Chicago, Chicago, Illinois
2Department of Psychiatry, University of Cambridge, Cambridge, England3Cambridge and Peterborough NHS Foundation Trust, Cambridge, England
JAMA Psychiatry. 2016;73(8):877-878. doi:10.1001/jamapsychiatry.2016.1452.
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...