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Comment & Response |

Use of Clozapine in Schizophrenia ONLINE FIRST

Feras Ali Mustafa, MD1
[+] Author Affiliations
1Northamptonshire Healthcare NHS Foundation Trust, Northampton, England
JAMA Psychiatry. Published online July 20, 2016. doi:10.1001/jamapsychiatry.2016.0976
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To the Editor Clozapine was not shown to be superior to other antipsychotic drugs in the comprehensive meta-analysis conducted by Samara et al.1 This finding is in stark contrast to the landmark randomized clinical trial by Kane et al,2 which has been backed by the cumulative wisdom of nearly 3 decades of clinical experience and observational evidence.

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July 20, 2016
Joseph P. McEvoy, MD
1Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta
JAMA Psychiatry. Published online July 20, 2016.;():. doi:10.1001/jamapsychiatry.2016.1241.
July 20, 2016
Myrto T. Samara, MD; Stefan Leucht, MD
1Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany
JAMA Psychiatry. Published online July 20, 2016.;():. doi:10.1001/jamapsychiatry.2016.1331.
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