We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
In This Issue of JAMA Psychiatry |

In This Issue FREE

JAMA Psychiatry. 2016;73(9):887. doi:10.1001/jamapsychiatry.2015.1648.
Text Size: A A A
Published online


The value of short-term dynamic psychotherapy in the treatment of major depression is a matter of debate. Connolly Gibbons and colleagues conducted a randomized noninferiority trial, comparing cognitive behavioral therapy and dynamic therapy in 237 adults with major depression treated in community mental health centers. Dynamic therapy was not inferior to cognitive behavioral therapy. In an editorial, Abbass and Town discuss the implications of this study for routine practice.

Research links childhood abuse to multiple adverse outcomes in adulthood, but little is known about association with all-cause mortality. Chen and colleagues studied a national sample of 6285 adults from the Midlife Development in the United States survey and found that women (but not men) who reported childhood emotional or physical abuse were at a significantly higher risk of all-cause mortality in adulthood. These results suggest that reported childhood abuse has long-term ramifications for health and longevity in women. In an editorial, Shalev and colleagues discuss implications for the field.

Antipsychotic-induced weight gain is a clinical challenge in the treatment of young people with autism spectrum disorders. Anagnostou and colleagues carried out a multicenter, 16-week double-blind randomized clinical trial to examine the impact of metformin on this condition. Metformin was associated with 3-kg lower weight and significantly reduced body mass index when compared with placebo; it was also well-tolerated except for some mild gastrointestinal symptoms. In an editorial, McDougle discusses strategies for treating antipsychotic-induced weight gain in children with autism spectrum disorder.

The frequency of antipsychotic medication use during pregnancy has doubled over the past decade. Huybrechts and colleagues studied a large cohort of Medicaid-insured pregnant women to assess the risk of congenital malformations overall and of cardiac malformations associated with antipsychotic medication use during the first trimester of pregnancy. The adjusted relative risk was not significantly increased, with the possible exception of risperidone. In an editorial, Wisner and colleagues discuss the use of antipsychotics in pregnancy.

Methylphenidate effectively treats attention-deficit/hyperactivity disorder, but the long-lasting effects on the brain are not well studied. Schrantee and colleagues measured cerebral blood flow changes in 99 male patients with attention-deficit/hyperactivity disorder during a 16-week randomized clinical trial of methylphenidate. Treatment with methylphenidate resulted in cerebral blood flow changes in thalamus and striatum of children, but not adults. This confirms evidence for age-dependent effects of methylphenidate treatment.





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Related Content

Customize your page view by dragging & repositioning the boxes below.