0
Letters to the Editor |

Androgen Replacement in a 48, XXYY-Male Patient

Isabella Heuser, MD; Andreas Hartmann, MD; Heide Oertel, MD
Arch Gen Psychiatry. 1999;56(2):194-195. doi:.
Text Size: A A A
Published online

Extract

A 32-year-old man was admitted to our institute in January 1995. A 48, XXYY karyotype had been diagnosed at the age of 6 years, subsequent to delayed speech development. Because of the primary hypergonadotrophic hypogonadism common in this disorder, androgen replacement was first considered in 1988. The rationale was to prevent somatic consequences of hypogonadism such as osteoporosis and muscle wasting. However, this proposal was discarded by a counseling psychiatrist because ". . . androgen replacement would be too risky considering the patient's labile personality structure. . . ." For similar reasons, 3 more clinics refused to initiate androgen replacement therapy. Six months prior to admission to the hospital, the patient developed increasing tiredness, sleeping 10 to 12 hours on weekdays and up to 16 hours on weekends. Therefore, he was finally referred to our institute for reevaluation of androgen replacement therapy.

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

February 1, 1999
Robert B. Zipursky, MD, FRCPC; Shitij Kapur, MD, PhD, FRCPC
Arch Gen Psychiatry. 1999;56(2):195-196. doi:.
CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 9

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Jobs
brightcove.createExperiences();