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Blood Glutathione and Eosinophil Levels and Hospital Adjustment Scale in Chronic Schizophrenia:  Studies over Periods of Four to Eight Months

MARK D. ALTSCHULE, M.D.; STANLEY H. ELDRED, M.D.; LEWIS J. SHERMAN, Ph.D.; JOSEPH N. GIANCOLA
AMA Arch Gen Psychiatry. 1959;1(4):358-365. doi:10.1001/archpsyc.1959.03590040028002.
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Eight chronic schizophrenic women have been transferred to a special research ward at the McLean Hospital during the past year; they have remained in this relatively stable environment for many months, receiving no special treatment but being subjected to clinical observation and to tests of different kinds. It is now possible to present data on seven of the patients so studied for periods of four to eight months; the eighth patient would not permit the taking of blood samples and is therefore not included in this study. The present report describes the findings with respect to clinical status, Hospital Adjustment Scale scores, blood eosinophil counts, and blood reduced-glutathione concentration.

Material and Methods

The blood eosinophil cells were counted at approximately weekly intervals, using the method previously described.12 The blood samples used were taken from an antecubital vein at about the same time of

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