Patients simultaneously exhibiting symptoms of hyperthyroidism and an overt psychosis have been seen sufficiently frequently in clinical practice to prompt many investigators to inquire into a possible relationship between the 2 sets of symptoms. There has been considerable diversity of opinion expressed on the subject. It is the purpose of this study to reexamine the relationship between these disease processes in the light of data gathered at a large county general hospital.* There will be a consideration of diagnostic and sampling problems, the incidence of the association of the 2 sets of symptoms, the types of psychoses seen in persons with hyperthyroidism, and the nature of the relationship between the 2 processes.
Diagnostic and Sampling Problems
It would be exceedingly difficult to obtain representative samples of populations with thyrotoxicosis and psychosis because many persons with these diseases do not come to the attention of