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14 and 6 CPS Positive EEG Spikes in a Family

Arch Gen Psychiatry. 1963;9(6):559-565. doi:10.1001/archpsyc.1963.01720180031005.
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In 1951, Gibbs and Gibbs,1 reporting on a study of 5,000 epileptics, described an abnormal electroencephalogram which occurred during sleep in 6% of their patients. Characteristically, the aberrant record consisted of abnormal spike activity, with a rate either of 14 or 6 spikes per second, the highest voltage usually occurring in the occipital and temporal areas. Since then, there have been numerous reports of this abnormality in the literature. A variety of symptoms has been described in these patients, including behavior disorders, autonomic dysfunctioning, headache, dizziness, and various epileptiform disorders. Kellaway et al2 found a history of head injury or encephalitis in a significant number (37% of 459 patients), and Hughes et al3 found that 40% of their 115 patients had a history of postnatal head injury. Walter et al4 found a correlation with "aggressive behavior," and Garneski5 found a high


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