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Walter Hirsch, MD
Arch Gen Psychiatry. 1963;9(6):633-635. doi:10.1001/archpsyc.1963.01720180105018.
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This book is dedicated to Asbjörn Fölling "who started this all," and whose name this disease should bear rather than that of phenylketonuria (PKU). (This would have avoided the paradoxical cases of "phenylketonuria without phenylpyruvic acid.")

Although there are only about 1,000 known cases to date the world over, the bearing that this rare disease has on biochemical and genetic principles, as well as therapy, makes such a monograph worthwhile.

Eleven authorities, each well known in his own field, have contributed the 11 chapters covering incidence and inheritance, the clinical picture, biochemistry, pathology, pathogenesis, detection, management, and animal experiments. As it is usual in such monographs, the value of the various chapters is not consistent.

The editor certainly had a difficult job, but the next edition could be improved by eliminating repetitions and by indicating references to the same matters in the course of the various chapters. The


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