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Behavioral Antecedents of Adult Schizophrenia:  A Review

David R. Offord, MD; Lucien A. Cross
Arch Gen Psychiatry. 1969;21(3):267-283. doi:10.1001/archpsyc.1969.01740210011003.
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AT A glance the literature on the behavioral antecedents of adult schizophrenia appears to be hopelessly contradictory, first suggesting that most preschizophrenics are withdrawn during childhood, then indicating that aggressive antisocial children are at high risk for serious psychiatric problems including schizophrenia as adults, and finally demonstrating that children of all behavioral types may become schizophrenics. The central issue is whether certain behavior patterns in childhood identify children who are at high risk for adult schizophrenia. If this were the case, it possibly would give us some clue about the etiology of the disorder and would allow us to identify and study groups of children with a high expectancy for adult schizophrenia before the overt onset of the disease.

This paper will review the literature on the behavioral antecedents of adult schizophrenia. While anterospective studies starting with a group of children

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