0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Manic-Depressive Illness, Diabetes Mellitus, and Lithium Carbonate

Christiaan D. van der Velde, MD; Malcolm W. Gordon, PhD
Arch Gen Psychiatry. 1969;21(4):478-485. doi:10.1001/archpsyc.1969.01740220094011.
Text Size: A A A
Published online

OUR interest in the glucose metabolism of manic-depressive patients originated with the discovery of a diabetic condition in a patient whose complaints of polyuria, thirst, fatigue, and spells of profuse perspiration were initially interpreted as toxic manifestations of lithium carbonate therapy. In addition to a diabetic response to the glucose tolerance tests, a review of her hospital record revealed high-fasting blood sugar levels on several previous admissions. Similar findings among other manic-depressive patients formed the rationale of the following studies.

Procedures  Repeated glucose tolerance tests were performed on 42 manic-depressive patients hospitalized at Norwich Hospital. The diagnoses of these patients were independently agreed upon by the referring hospital and research staff, and confirmed by their past histories as documented in their hospital records. Most of these patients were readmissions and not on medication. Some patients were receiving lithium carbonate.A second glucose tolerance survey was carried out on

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();