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Psychomotor Activity in Mania

Brian L. Weiss, MD; F. Gordon Foster, MD; Charles F. Reynolds III, MD; David J. Kupfer, MD
Arch Gen Psychiatry. 1974;31(3):379-383. doi:10.1001/archpsyc.1974.01760150083012.
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This study investigates the levels of psychomotor activity during mania and attempts to assess the effects of lithium carbonate and clinical change on activity levels. Activity data were collected continuously by means of a telemetric mobility-sensing system.

The study was divided into three sections: the monitoring of three manic patients during a pretreatment base line period; the study of six bipolar patients before and during lithium carbonate treatment: and the intensive longitudinal investigation of a manic patient over a five-month period.

Results indicate that both the quantity and patterning of manic activity were substantially different from other diagnostic groups previously studied. Activity levels do not appear to be affected by the use of lithium carbonate, unless associated with clinical change.

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