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Article |

Memory Functions in Depression:  Improvement With Antidepressant Medication

David E. Sternberg, MD; Murray E. Jarvik, MD
Arch Gen Psychiatry. 1976;33(2):219-224. doi:10.1001/archpsyc.1976.01770020055009.
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•In an attempt to elucidate the memory deficit in depression, short-term memory and long-term memory were examined by means of a memory test battery in 26 hospitalized depressed patients. Their performance was compared with a matched control group and with the performance of those 20 patients who improved after 26 days of treatment with antidepressants. Results Indicate that depressed patients show marked impairment in short-term memory without an impairment in long-term memory. The greater the improvement of the clinical state, the greater the Improvement In short-term memory, whereas long-term memory was not influenced by the therapeutic success.

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