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Incidence and Severity of Tardive Dyskinesia Increase With Age

G.F.S. Johnson, MD; G. E. Hunt, MD; J. M. Rey, MD
Arch Gen Psychiatry. 1982;39(4):486. doi:10.1001/archpsyc.1982.04290040080012.
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To the Editor  —We recently completed an assessment of tardive dyskinesia (TD) in psychiatric outpatients using the Abnormal Involuntary Movement Scale (AIMS).1 In light of Smith and Baldessarini's report of a strong correlation between severity of TD and age (Archives 1980;37:1368-1373), we investigated this relationship in our sample population. The patients (n = 66) assessed were those who regularly attended a community health center in Sydney, Australia. Fifty had a diagnosis of schizophrenia, four of manic-depressive illness, and 12 of other illnesses, such as personality disorder, neurosis, etc. Most of the patients had regularly received fluphenazie decanoate (Modecate) by intramuscular injection for up to two years before assessment; only four patients had never received neuroleptic drugs.There was a tendency for TD (considered present if there was a rating of 2 in any body area) to increase with age, because patients over the age of 45 years (n = 34) had a higher prevalence of TD (56%) than those below age 45 years

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